We believe evidence is a duty, not a chore
Our digital therapeutics aren’t just based on science: They’ve been proven effective in gold-standard clinical trials.
Setting the standard for rigorous clinical evidence
We believe digital therapeutics must be put to the test as rigorously as traditional medicine. People’s mental health depends on it. That belief not only fuels our commitment to clinical evidence — it also drives our efforts to make research more equitable for underserved populations.
Randomized controlled trials (RCTs)
Clinical guideline citations1-4
Sleepio helped 76% of patients achieve clinical improvement in insomnia
In the world’s ﬁrst placebo-controlled trial for a digital therapeutic, Sleepio was shown to be significantly more effective than the placebo. After six weeks, 76% of Sleepio users achieved clinical improvement in insomnia.5
Daylight helped 71% of patients achieve clinical improvement in anxiety
In a landmark study, Daylight demonstrated significantly greater reductions in symptoms of clinical anxiety than the control condition. After 10 weeks, 71% of Daylight users moved from clinical to non-clinical levels of anxiety, as compared to 33% of those in the control group.6
Research conducted with world-class partners
Our digital therapeutics are clinically evaluated in partnership with leading research institutions and the studies are published in top peer-reviewed journals to ensure quality and transparency.
The effects of dCBT for insomnia on cognitive functionRead paper
Efficacy of dCBT for moderate-to-severe symptoms of generalized anxiety disorderRead paper
A randomized controlled trial of dCBT for insomnia in pregnant womenRead paper
Efficacy of dCBT for the treatment of insomnia symptoms among pregnant womenRead paper
A pilot RCT for dCBT for sub-threshold insomniaRead paper
RCT on impact of dCBT for insomnia on health, wellbeing, and quality of lifeRead paper
Efficacy of dCBT for insomnia to improve depression across demographic groupsRead paper
The effects of improving sleep on mental health (OASIS)Read paper
Sleep to lower elevated blood pressure (SLEPT)Read paper
Helping employees sleep well: effects of CBT for insomnia on work outcomesRead paper
Sleep and productivity benefits of digital CBTiRead paper
The anxiolytic effects of cognitive behavior therapy for insomniaRead paper
RCT of placebo controlled dCBT for chronic insomnia disorderRead paper
1. Qaseem, A., Kansagara, D., Forciea, M. A., Cooke, M., & Denberg, T. D. (2016). Management of chronic insomnia disorder in adults: a clinical practice guideline from the American College of Physicians. Annals of Internal Medicine, 165(2), 125-133.
2. Riemann, D., Baglioni, C., Bassetti, C., Bjorvatn, B., Dolenc Groselj, L., Ellis, J. G., … & Spiegelhalder, K. (2017). European guideline for the diagnosis and treatment of insomnia. Journal of Sleep Research, 26(6), 675-700.
3. Wilson, S., Anderson, K., Baldwin, D., Dijk, D. J., Espie, A., Espie, C., … & Sharpley, A. (2019). British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders: an update. Journal of Psychopharmacology, 33(8), 923-947.
4. King’s Technology Evaluation Centre. (2017, November 9). Overview: Health app: SLEEPIO for adults with poor Sleep: Advice. NICE. https://www.nice.org.uk/advice/mib129.
5. Carl, J. R., Miller, C. B., Henry, A. L., Davis, M. L., Stott, R., Smits, J. A., … & Espie, C. A. (2020). Efficacy of digital cognitive behavioral therapy for moderate‐to‐severe symptoms of generalized anxiety disorder: A randomized controlled trial. Depression and Anxiety, 37(12), 1168-1178.
6. Espie, C. A., Kyle, S. D., Williams, C., Ong, J. C., Douglas, N. J., Hames, P., & Brown, J. S. (2012). A randomized, placebo-controlled trial of online cognitive behavioral therapy for chronic insomnia disorder delivered via an automated media-rich web application. Sleep, 35(6), 769-781.