We believe evidence is a duty, not a chore

Our digital treatments aren’t just based on science: They’ve been proven effective in gold-standard clinical trials.

Setting the standard for rigorous clinical evidence

We believe digital treatments must be put to the test as rigorously as traditional medicine. People’s mental health depends on it. That belief not only fuels our commitment to clinical evidence — it also drives our efforts to make research more equitable for underserved populations.

75

Peer-reviewed publications

14

Randomized controlled trials (RCTs)

28k+

Participants across all evidence papers

4

Sleepio references in clinical guidelines1-4

Sleepio helped 76% of patients achieve clinical improvement in insomnia

In the world’s first placebo-controlled trial for a digital treatment, Sleepio was shown to be significantly more effective than the placebo. After six weeks, 76% of Sleepio users achieved clinical improvement in insomnia.5

Daylight helped 71% of patients achieve clinical improvement in anxiety

In a landmark study, Daylight demonstrated significantly greater reductions in symptoms of clinical anxiety than the control condition. After 10 weeks, 71% of Daylight patients moved from clinical to non-clinical levels of anxiety, as compared to 33% of those in the control group.6

Featured studies

Sleep and Productivity Benefits of Digital Cognitive Behavioral Therapy for Insomnia: A Randomized Controlled Trial Conducted in the Workplace Environment

Bostock et al. (2016)
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JOEM
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Helping employees sleep well: Effects of cognitive behavioral therapy for insomnia on work outcomes

Barnes et al. (2017)
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Journal of Applied Psychology
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Sleep to Lower Elevated Blood Pressure: A Randomized Controlled Trial (SLEPT)

McGrath et al. (2017)
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American Journal of Hypertension
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The effects of improving sleep on mental health (OASIS): a randomised controlled trial with mediation analysis

Freeman et al. (2017)
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Lancet Psychiatry
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Effect of Digital Cognitive Behavioral Therapy for Insomnia on Health, Psychological Well-being, and Sleep-Related Quality of Life: A Randomized Clinical Trial

Espie et al. (2019)
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JAMA Psychiatry
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Efficacy of digital CBT for insomnia to reduce depression across demographic groups: a randomized trial

Cheng et al. (2019)
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Psychological Medicine
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Is digital cognitive behavioural therapy for insomnia effective in treating sub-threshold insomnia: a pilot RCT

Denis et al. (2019)
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Sleep Medicine
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Efficacy of Digital Cognitive Behavioral Therapy for the Treatment of Insomnia Symptoms Among Pregnant Women: A Randomized Clinical Trial

Felder et al. (2020)
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JAMA Psychiatry
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A randomized controlled trial of digital cognitive behavioral therapy for insomnia in pregnant women

Kalmbach et al. (2020)
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Sleep Medicine
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Efficacy of digital cognitive behavioral therapy for moderate-to-severe symptoms of generalized anxiety disorder: A randomized controlled trial

Carl et al. (2020)
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Depression & Anxiety
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The effects of digital cognitive behavioral therapy for insomnia on cognitive function: a randomized controlled trial

Kyle et al. (2020)
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SLEEP
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Efficacy of a digital cognitive behavioral therapy for insomnia in people with low back pain: a feasibility randomized co-twin and singleton-controlled trial

Ho et al. (2022)
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Pilot and Feasibility Studies
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Improving sleep after stroke: A randomised controlled trial of digital cognitive behavioural therapy for insomnia

Fleming et al. (2023)
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Journal of Sleep Research
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1. Qaseem, A., Kansagara, D., Forciea, M. A., Cooke, M., & Denberg, T. D. (2016). Management of chronic insomnia disorder in adults: a clinical practice guideline from the American College of Physicians. Annals of Internal Medicine, 165(2), 125-133.
2. Riemann, D., Baglioni, C., Bassetti, C., Bjorvatn, B., Dolenc Groselj, L., Ellis, J. G., … & Spiegelhalder, K. (2017). European guideline for the diagnosis and treatment of insomnia. Journal of Sleep Research, 26(6), 675-700.
3. Wilson, S., Anderson, K., Baldwin, D., Dijk, D. J., Espie, A., Espie, C., … & Sharpley, A. (2019). British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders: an update. Journal of Psychopharmacology, 33(8), 923-947.
4. King’s Technology Evaluation Centre. (2017, November 9). Overview: Health app: SLEEPIO for adults with poor Sleep: Advice. NICE. https://www.nice.org.uk/advice/mib129.
5. Espie, C. A., Kyle, S. D., Williams, C., Ong, J. C., Douglas, N. J., Hames, P., & Brown, J. S. (2012). A randomized, placebo-controlled trial of online cognitive behavioral therapy for chronic insomnia disorder delivered via an automated media-rich web application. Sleep, 35(6), 769-781.
6. Carl, J. R., Miller, C. B., Henry, A. L., Davis, M. L., Stott, R., Smits, J. A., … & Espie, C. A. (2020). Efficacy of digital cognitive behavioral therapy for moderate‐to‐severe symptoms of generalized anxiety disorder: A randomized controlled trial. Depression and Anxiety, 37(12), 1168-1178.